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Effects of isoprenaline and aminophylline on the chronotropic responses of the isolated guinea-pig heart to vagal stimulation and acetylcholine
1. In isolated perfused guinea-pig hearts, isoprenaline (2 × 10(-8) g/ml) reduced the negative chronotropic responses to vagal stimulation and to exogenous acetylcholine. 2. The β-adrenoceptor antagonist LB46 (2 × 10(-8) g/ml) abolished the effect of isoprenaline in reducing vagal bradycardia. LB46...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1971
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665667/ https://ncbi.nlm.nih.gov/pubmed/4397803 |
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