Exon 3 β-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome

Background and aim: Activating β-catenin mutations in exon 3 have been implicated in colorectal tumorigenesis. Although reports to the contrary exist, it has been suggested that β-catenin mutations occur more often in microsatellite unstable (MSI+) colorectal carcinomas, including hereditary non-pol...

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Main Authors: Johnson, V, Volikos, E, Halford, S E, Eftekhar Sadat, E T, Popat, S, Talbot, I, Truninger, K, Martin, J, Jass, J, Houlston, R, Atkin, W, Tomlinson, I P M, Silver, A R J
格式: Artigo
語言:Inglês
出版: Copyright 2005 by Gut 2005
主題:
Colorectal Cancer
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774848/
https://ncbi.nlm.nih.gov/pubmed/15647192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.048132
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