Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome

We examined adenomas and cancers from hereditary non-polyposis colorectal cancer (HNPCC) syndrome patients for the presence of frameshift mutations in the smooth-muscle myosin gene, MYH11. Our results show that mutations in MYH11 occur more frequently in cancers than adenomas (P=0.008) and are depen...

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Detalhes bibliográficos
Main Authors: Vickaryous, N, Polanco-Echeverry, G, Morrow, S, Suraweera, N, Thomas, H, Tomlinson, I, Silver, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584943/
https://ncbi.nlm.nih.gov/pubmed/18941465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604737
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