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Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2

Background: Angiotensin converting enzyme (ACE) 2 is a recently identified homologue of ACE that may counterregulate the actions of angiotensin (Ang) II by facilitating its breakdown to Ang 1–7. The renin-angiotensin system (RAS) has been implicated in the pathogenesis of cirrhosis but the role of A...

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Detalhes bibliográficos
Main Authors: Paizis, G, Tikellis, C, Cooper, M E, Schembri, J M, Lew, R A, Smith, A I, Shaw, T, Warner, F J, Zuilli, A, Burrell, L M, Angus, P W
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Gut 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774784/
https://ncbi.nlm.nih.gov/pubmed/16166274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.062398
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