Osteopontin/Eta-1 upregulated in Crohn’s disease regulates the Th1 immune response

Background and aims: The pathogenesis of Crohn’s disease (CD), a chronic inflammatory bowel disease characterised by a Th1 immune response, remains unclear. Osteopontin (OPN) is a phosphoprotein known as an adhesive bone matrix protein. Recent studies have shown that OPN plays an important role in l...

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Detalhes bibliográficos
Main Authors: Sato, T, Nakai, T, Tamura, N, Okamoto, S, Matsuoka, K, Sakuraba, A, Fukushima, T, Uede, T, Hibi, T
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Gut 2005
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774642/
https://ncbi.nlm.nih.gov/pubmed/16099792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.048298
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