Chondrogenic Activity of the Heparan Sulfate Proteoglycan Perlecan Maps to the N-terminal Domain I

C3H10T1/2 cells differentiate along a chondrogenic pathway when plated onto the extracellular matrix (ECM) protein perlecan (Pln). To identify the region(s) within the large Pln molecule that provides a differentiation signal, recombinant Pln-sequence-based polypeptides representing distinct structu...

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Autori principali: FRENCH, MARGARET M., GOMES, RONALD R., TIMPL, RUPERT, HÖÖK, MAGNUS, CZYMMEK, KIRK, FARACH-CARSON, MARY C., CARSON, DANIEL D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774590/
https://ncbi.nlm.nih.gov/pubmed/11771669
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