INSULIN-LIKE GROWTH FACTOR TYPE 1 RECEPTOR SIGNALING IN THE CELLS OF OLIGODENDROCYTE LINEAGE IS REQUIRED FOR NORMAL IN VIVO OLIGODENDROCYTE DEVELOPMENT AND MYELINATION

Insulin-like growth factor-I (IGF-I) has been shown to be a potent agent in promoting the growth and differentiation of oligodendrocyte precursors, and in stimulating myelination during development and following injury. To definitively determine whether IGF-I acts directly on the cells of oligodendr...

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Main Authors: Zeger, Martha, Popken, Greg, Zhang, Jihui, Xuan, Shouhong, Lu, Q. Richard, Schwab, Markus H., Nave, Klaus-Armin, Rowitch, David, D’Ercole, A. Joseph, Ye, Ping
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774584/
https://ncbi.nlm.nih.gov/pubmed/17186502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20469
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