Increased epithelial uptake of protein antigens in the ileum of Crohn’s disease mediated by tumour necrosis factor α

Background and aims: The exact nature of the epithelial barrier defect in Crohn’s disease remains to be elucidated. Previously we showed increased permeability to proteins in ileal Crohn’s disease. Our aims were to study if this barrier defect (a) involves endocytotic uptake of antigens and (b) is r...

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Библиографические подробности
Главные авторы: Söderholm, J D, Streutker, C, Yang, P-C, Paterson, C, Singh, P K, McKay, D M, Sherman, P M, Croitoru, K, Perdue, M H
Формат: Artigo
Язык:Inglês
Опубликовано: Copyright 2004 by Gut 2004
Предметы:
Inflammatory Bowel Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774309/
https://ncbi.nlm.nih.gov/pubmed/15542521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.041426
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