Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity

Because hematopoietic stem cells are rich in aldehyde dehydrogenase (ALDH) activity, we developed a fluorescent substrate for ALDH, termed BODIPY aminoacetaldehyde (BAAA), and tested its potential for isolating primitive human hematopoietic cells. A population of cells with low orthogonal light scat...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Storms, Robert W., Trujillo, Aliana P., Springer, James B., Shah, Lisa, Colvin, O. Michael, Ludeman, Susan M., Smith, Clay
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1999
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10430905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.16.9118
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