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Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity

Because hematopoietic stem cells are rich in aldehyde dehydrogenase (ALDH) activity, we developed a fluorescent substrate for ALDH, termed BODIPY aminoacetaldehyde (BAAA), and tested its potential for isolating primitive human hematopoietic cells. A population of cells with low orthogonal light scat...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Storms, Robert W., Trujillo, Aliana P., Springer, James B., Shah, Lisa, Colvin, O. Michael, Ludeman, Susan M., Smith, Clay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1999
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17742/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10430905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.16.9118
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