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Increased DMT1 but not IREG1 or HFE mRNA following iron depletion therapy in hereditary haemochromatosis

Background and aims: While upregulation of divalent metal transporter 1 (DMT1) and iron regulated gene 1 (IREG1) within duodenal enterocytes is reported in patients with hereditary haemochromatosis (HH), these findings are controversial. Furthermore, the effect of HFE, the gene mutated in HH, on exp...

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Autori principali: Kelleher, T, Ryan, E, Barrett, S, Sweeney, M, Byrnes, V, O’Keane, C, Crowe, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2004 by Gut 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774138/
https://ncbi.nlm.nih.gov/pubmed/15247188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.033811
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