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Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro
Background: Overexpression of tissue plasminogen activator (t-PA) in pancreatic cancer cells promotes invasion and proliferation in vitro and tumour growth and angiogenesis in vivo. Aims: To understand the mechanisms by which t-PA favours cancer progression, we analysed the surface membrane proteins...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2004 by Gut
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1774091/ https://ncbi.nlm.nih.gov/pubmed/15194650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2003.026831 |
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