Hereditary diffuse gastric cancer: predominance of multiple foci of signet ring cell carcinoma in distal stomach and transitional zone

Background and aims: Germline mutations in the CDH-1/E-cadherin gene are, to date, the only known cause of hereditary diffuse gastric cancer (HDGC). While two recent series of prophylactic gastrectomy described microscopic foci of signet ring cell carcinoma in sample sections from 10 macroscopically...

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Bibliografiske detaljer
Main Authors: Charlton, A, Blair, V, Shaw, D, Parry, S, Guilford, P, Martin, I G
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2004 by Gut 2004
Fag:
Stomach
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774074/
https://ncbi.nlm.nih.gov/pubmed/15138207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2002.010447
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