Inducible CD40 expression mediates NFκB activation and cytokine secretion in human colonic fibroblasts

Background: CD40 has been shown to be a functional activation antigen on a variety of cell types involved in immune responses. As intestinal fibroblasts and myofibroblasts may play a role during mucosal inflammation, we investigated the functional consequences of CD40 induction in primary cultures o...

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Hauptverfasser: Gelbmann, C M, Leeb, S N, Vogl, D, Maendel, M, Herfarth, H, Schölmerich, J, Falk, W, Rogler, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2003 by Gut 2003
Schlagworte:
Inflammation and Inflammatory Bowel Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773835/
https://ncbi.nlm.nih.gov/pubmed/12970138
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