The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development

Background: During development, the homeobox gene Cdx2 exerts a homeotic function, providing the positional information necessary for correct specification of the midgut endoderm. This is illustrated by the non-neoplastic gastric-type heteroplasias present at birth in the pericaecal region of Cdx2(+...

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Detalhes bibliográficos
Main Authors: Bonhomme, C, Duluc, I, Martin, E, Chawengsaksophak, K, Chenard, M-P, Kedinger, M, Beck, F, Freund, J-N, Domon-Dell, C
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by Gut 2003
Assuntos:
Colon
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773830/
https://ncbi.nlm.nih.gov/pubmed/12970140
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