p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential

p21(WAF1/Cip1) is one of the best characterized downstream targets of p53, and the growth suppressing function of this cyclin-dependent kinase inhibitor is well established. However, whether p21 exerts a tumor-suppressing function of its own remains to be established. We report here that, similarly...

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Bibliographic Details
Main Authors: Topley, Gabrielle I., Okuyama, Ryuhei, Gonzales, José G., Conti, Claudio, Dotto, G. Paolo
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17737/
https://ncbi.nlm.nih.gov/pubmed/10430900
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