CARD15/NOD2 gene variants are associated with familially occurring and complicated forms of Crohn’s disease

Background: Variants of the caspase activating recruitment domain 15/nucleotide oligomerisation domain 2 (CARD15/NOD2) gene have been associated with susceptibility to Crohn’s disease (CD). Aim: Our aim was to evaluate the allele frequencies of the CARD15 variants R702W, G908R, and 1007fs in Finnish...

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Main Authors: Heliö, T, Halme, L, Lappalainen, M, Fodstad, H, Paavola-Sakki, P, Turunen, U, Färkkilä, M, Krusius, T, Kontula, K
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2003 by Gut 2003
Fag:
Inflammatory Bowel Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773614/
https://ncbi.nlm.nih.gov/pubmed/12631669
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