In vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats

Background: Portal hypertension in cirrhosis results from enhanced intrahepatic resistance to an augmented inflow. The former is partly due to an imbalance between intrahepatic vasoconstriction and vasodilatation. Enhanced endothelin-1 and decreased activity of hepatic constitutive endothelial nitri...

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Hauptverfasser: Van de Casteele, M, Omasta, A, Janssens, S, Roskams, T, Desmet, V, Nevens, F, Fevery, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2002 by Gut 2002
Schlagworte:
Liver Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773350/
https://ncbi.nlm.nih.gov/pubmed/12171971
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