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TPMT in the treatment of Crohn's disease with azathioprine

Azathioprine induced profound myelosuppression linked to TPMT deficiency has now been documented in many patient groups, including those with Crohn's disease. At the start of azathioprine or mercaptopurine therapy, measurement of TPMT activity has a role in identifying the 1 in 300 patients who...

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Autore principale: Lennard, L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2002 by Gut 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773327/
https://ncbi.nlm.nih.gov/pubmed/12117866
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