Tumour necrosis factor α converting enzyme (TACE) activity in the colonic mucosa of patients with inflammatory bowel disease

Background: Anti-tumour necrosis factor α (TNF-α) antibodies are effective in Crohn's disease and perhaps ulcerative colitis but antigenicity and the high cost have raised interest in other strategies to block TNF-α. These include the TNF-α converting enzyme (TACE) which releases soluble TNF-α...

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Bibliographische Detailangaben
Hauptverfasser: Brynskov, J, Foegh, P, Pedersen, G, Ellervik, C, Kirkegaard, T, Bingham, A, Saermark, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2002 by Gut 2002
Schlagworte:
Inflammatory Bowel Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773288/
https://ncbi.nlm.nih.gov/pubmed/12077089
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