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Thalidomide reduces tumour necrosis factor α and interleukin 12 production in patients with chronic active Crohn's disease

Background: Thalidomide improves clinical symptoms in patients with therapy refractory Crohn's disease, as shown in two recent studies. The mechanism of this effect however is still unknown. Suppression of tumour necrosis factor α (TNF-α) by thalidomide has been suggested as a possible mechanis...

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Main Authors: Bauditz, J, Wedel, S, Lochs, H
Formato: Artigo
Idioma:Inglês
Publicado: Copyright 2002 by Gut 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773116/
https://ncbi.nlm.nih.gov/pubmed/11788559
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