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Thalidomide reduces tumour necrosis factor α and interleukin 12 production in patients with chronic active Crohn's disease

Background: Thalidomide improves clinical symptoms in patients with therapy refractory Crohn's disease, as shown in two recent studies. The mechanism of this effect however is still unknown. Suppression of tumour necrosis factor α (TNF-α) by thalidomide has been suggested as a possible mechanis...

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Detalhes bibliográficos
Main Authors: Bauditz, J, Wedel, S, Lochs, H
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 by Gut 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773116/
https://ncbi.nlm.nih.gov/pubmed/11788559
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