Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease

Background and aims: Treatment with infliximab induces remission in about 70% of patients with steroid refractory Crohn's disease. Because Crohn's disease is considered to be mediated by uncontrolled activation of mucosal T lymphocytes, we hypothesised that infliximab could induce apoptosi...

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Hauptverfasser: ten Hove, T, van Montfrans, C, Peppelenbosch, M P, van Deventer, S J H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2002 by Gut 2002
Schlagworte:
Inflammation and Inflammatory Bowel Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773100/
https://ncbi.nlm.nih.gov/pubmed/11788561
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