Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon γ

Background: Interleukin 10 (IL-10) exerts anti-inflammatory actions by counteracting many biological effects of interferon γ (IFN-γ). Aims: To investigate this in humans, we studied the effects of human recombinant IL-10 administration on IFN-γ production by patient leucocytes. Furthermore, we asses...

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Autors principals: Tilg, H, van Montfrans, C, van den Ende, A, Kaser, A, van Deventer, S J H, Schreiber, S, Gregor, M, Ludwiczek, O, Rutgeerts, P, Gasche, C, Koningsberger, J C, Abreu, L, Kuhn, I, Cohard, M, LeBeaut, A, Grint, P, Weiss, G
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2002 by Gut 2002
Matèries:
Inflammation and Inflammatory Bowel Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773093/
https://ncbi.nlm.nih.gov/pubmed/11788558
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