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Purification of the two-enzyme system catalyzing the oxidation of the D-proline residue of pristinamycin IIB during the last step of pristinamycin IIA biosynthesis.

High levels of conversion of 14C-labelled pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA) were obtained in vivo in Streptomyces pristinaespiralis and in some other streptogramin A producers. This established that PIIB was an intermediate on the pathway to PIIA. In addition, in vitro studies wit...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thibaut, D, Ratet, N, Bisch, D, Faucher, D, Debussche, L, Blanche, F
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1995
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC177309/
https://ncbi.nlm.nih.gov/pubmed/7665508
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