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Purification of the two-enzyme system catalyzing the oxidation of the D-proline residue of pristinamycin IIB during the last step of pristinamycin IIA biosynthesis.

High levels of conversion of 14C-labelled pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA) were obtained in vivo in Streptomyces pristinaespiralis and in some other streptogramin A producers. This established that PIIB was an intermediate on the pathway to PIIA. In addition, in vitro studies wit...

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Bibliografiska uppgifter
I publikationen:J Bacteriol
Huvudupphov: Thibaut, D, Ratet, N, Bisch, D, Faucher, D, Debussche, L, Blanche, F
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1995
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7665508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.18.5199-5205.1995
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