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Pharmacophore-based discovery of ligands for drug transporters

The ability to identify ligands for drug transporters is an important step in drug discovery and development. It can both improve accurate profiling of lead pharmacokinetic properties and assist in the discovery of new chemical entities targeting transporters. In silico approaches, especially pharma...

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Hlavní autoři: Chang, Cheng, Ekins, Sean, Bahadduri, Praveen, Swaan, Peter W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773055/
https://ncbi.nlm.nih.gov/pubmed/17097188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2006.09.006
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