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Pharmacophore-based discovery of ligands for drug transporters

The ability to identify ligands for drug transporters is an important step in drug discovery and development. It can both improve accurate profiling of lead pharmacokinetic properties and assist in the discovery of new chemical entities targeting transporters. In silico approaches, especially pharma...

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Detalhes bibliográficos
Main Authors: Chang, Cheng, Ekins, Sean, Bahadduri, Praveen, Swaan, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773055/
https://ncbi.nlm.nih.gov/pubmed/17097188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2006.09.006
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