Multicopy suppression of cold-sensitive sec mutations in Escherichia coli.

Mutations in the secretory (sec) genes in Escherichia coli compromise protein translocation across the inner membrane and often confer conditional-lethal phenotypes. We have found that overproduction of the chaperonins GroES and GroEL from a multicopy plasmid suppresses a wide array of cold-sensitiv...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Danese, P N, Murphy, C K, Silhavy, T J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC177272/
https://ncbi.nlm.nih.gov/pubmed/7665473
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