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Multicopy suppression of cold-sensitive sec mutations in Escherichia coli.

Mutations in the secretory (sec) genes in Escherichia coli compromise protein translocation across the inner membrane and often confer conditional-lethal phenotypes. We have found that overproduction of the chaperonins GroES and GroEL from a multicopy plasmid suppresses a wide array of cold-sensitiv...

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Udgivet i:J Bacteriol
Principais autores: Danese, P N, Murphy, C K, Silhavy, T J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7665473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.17.4969-4973.1995
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