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Senescence associated β galactosidase activity in human retinal pigment epithelial cells exposed to mild hyperoxia in vitro

Aims: To determine if mild hyperoxia induces senescence in retinal pigment epithelium (RPE) cells in vitro. Methods: RPE340 cells and WI38 cells were grown in 20% oxygen and 40% oxygen until proliferative exhaustion. A combined senescence associated β galactosidase (SABG) and 5-bromo-2`-deoxyuridine...

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Detalhes bibliográficos
Main Authors: Honda, Shigeru, Hjelmeland, Leonard M, Handa, James T
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2002 British Journal of Ophthalmology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1771010/
https://ncbi.nlm.nih.gov/pubmed/11815340
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