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The APC/C inhibitor, Emi1, is essential for prevention of rereplication

Emi1 (early mitotic inhibitor) inhibits APC/C (anaphase-promoting complex/cyclosome) activity during S and G2 phases, and is believed to be required for proper mitotic entry. We report that Emi1 plays an essential function in cell proliferation by preventing rereplication. Rereplication seen after E...

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Detalhes bibliográficos
Main Authors: Machida, Yuichi J., Dutta, Anindya
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770901/
https://ncbi.nlm.nih.gov/pubmed/17234884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1495007
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