UmuD′(2)C is an error-prone DNA polymerase, Escherichia coli pol V

The damage-inducible UmuD′ and UmuC proteins are required for most SOS mutagenesis in Escherichia coli. Our recent assay to reconstitute this process in vitro, using a native UmuD′(2)C complex, revealed that the highly purified preparation contained DNA polymerase activity. Here we eliminate the pos...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Tang, Mengjia, Shen, Xuan, Frank, Ekaterina G., O’Donnell, Mike, Woodgate, Roger, Goodman, Myron F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10430871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.16.8919
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