UmuD′(2)C is an error-prone DNA polymerase, Escherichia coli pol V

The damage-inducible UmuD′ and UmuC proteins are required for most SOS mutagenesis in Escherichia coli. Our recent assay to reconstitute this process in vitro, using a native UmuD′(2)C complex, revealed that the highly purified preparation contained DNA polymerase activity. Here we eliminate the pos...

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Autores principales: Tang, Mengjia, Shen, Xuan, Frank, Ekaterina G., O’Donnell, Mike, Woodgate, Roger, Goodman, Myron F.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1999
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC17708/
https://ncbi.nlm.nih.gov/pubmed/10430871
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