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The major role of Spo0A in genetic competence is to downregulate abrB, an essential competence gene.

We show that the major role for Spo0A in the development of genetic competence is to downregulate expression of abrB. AbrB is both a negative regulator and a positive regulator of competence. The negative effects are exerted at multiple points in competence regulation. A regulatory mechanism that is...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Hahn, J, Roggiani, M, Dubnau, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7768874/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.12.3601-3605.1995
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