The major role of Spo0A in genetic competence is to downregulate abrB, an essential competence gene.

We show that the major role for Spo0A in the development of genetic competence is to downregulate expression of abrB. AbrB is both a negative regulator and a positive regulator of competence. The negative effects are exerted at multiple points in competence regulation. A regulatory mechanism that is...

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Vydáno v:	J Bacteriol
Hlavní autoři:	Hahn, J, Roggiani, M, Dubnau, D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1995
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC177070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7768874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.12.3601-3605.1995
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