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Resistance to scrapie in PrP ARR/ARQ heterozygous sheep is not caused by preferential allelic use
Background: In sheep, susceptibility to scrapie, which is similar to human prion diseases such as Kuru and variant Creutzfeldt-Jakob disease (vCJD), is determined by prion protein (PrP) gene (Prnp) polymorphisms. Sheep with genotype ARQ/ARQ, denoting polymorphisms at codons 136, 154, and 171, are su...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Copyright 2004 Journal of Clinical Pathology
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1770315/ https://ncbi.nlm.nih.gov/pubmed/15166274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2003.012203 |
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