Resistance to scrapie in PrP ARR/ARQ heterozygous sheep is not caused by preferential allelic use

Background: In sheep, susceptibility to scrapie, which is similar to human prion diseases such as Kuru and variant Creutzfeldt-Jakob disease (vCJD), is determined by prion protein (PrP) gene (Prnp) polymorphisms. Sheep with genotype ARQ/ARQ, denoting polymorphisms at codons 136, 154, and 171, are su...

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Detaylı Bibliyografya
Asıl Yazarlar: Caplazi, P A, O’Rourke, K I, Baszler, T V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Copyright 2004 Journal of Clinical Pathology 2004
Konular:
Short Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770315/
https://ncbi.nlm.nih.gov/pubmed/15166274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2003.012203
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