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Loss of nuclear expression of the p33(ING1b) inhibitor of growth protein in childhood acute lymphoblastic leukaemia

Background/Aims: p33(ING1b) is a tumour suppressor protein involved in growth control and apoptosis. Suppression of p33(ING1b) expression is associated with the loss of cellular growth control and immortalisation, whereas its overexpression causes cell cycle arrest. Moreover, normal p33(ING1b) expre...

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Autors principals: Nouman, G S, Anderson, J J, Wood, K M, Lunec, J, Hall, A G, Reid, M M, Angus, B
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2002 Journal of Clinical Pathology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769716/
https://ncbi.nlm.nih.gov/pubmed/12147653
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