Potent urea and carbamate inhibitors of soluble epoxide hydrolases

The soluble epoxide hydrolase (sEH) plays a significant role in the biosynthesis of inflammation mediators as well as xenobiotic transformations. Herein, we report the discovery of substituted ureas and carbamates as potent inhibitors of sEH. Some of these selective, competitive tight-binding inhibi...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Morisseau, Christophe, Goodrow, Marvin H., Dowdy, Deanna, Zheng, Jiang, Greene, Jessica F., Sanborn, James R., Hammock, Bruce D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC17696/
https://ncbi.nlm.nih.gov/pubmed/10430859
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller