A Mouse-Adapted SARS-Coronavirus Causes Disease and Mortality in BALB/c Mice

No single animal model for severe acute respiratory syndrome (SARS) reproduces all aspects of the human disease. Young inbred mice support SARS-coronavirus (SARS-CoV) replication in the respiratory tract and are available in sufficient numbers for statistical evaluation. They are relatively inexpens...

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Detalhes bibliográficos
Main Authors: Roberts, Anjeanette, Deming, Damon, Paddock, Christopher D, Cheng, Aaron, Yount, Boyd, Vogel, Leatrice, Herman, Brian D, Sheahan, Tim, Heise, Mark, Genrich, Gillian L, Zaki, Sherif R, Baric, Ralph, Subbarao, Kanta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769406/
https://ncbi.nlm.nih.gov/pubmed/17222058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030005
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