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Reduced cardiac expression of plasminogen activator inhibitor 1 and transforming growth factor β(1) in obese Zucker rats by perindopril

Objective: To determine whether angiotensin converting enzyme inhibition by perindopril can reduce cardiac transforming growth factor β1 (TGFβ1) and plasminogen activator inhibitor 1 (PAI-1) and therefore control collagen accumulation in an animal model with the metabolic syndrome such as the obese...

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Detalhes bibliográficos
Main Authors: Toblli, J E, Cao, G, DeRosa, G, Forcada, P
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by Heart 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1768649/
https://ncbi.nlm.nih.gov/pubmed/15604340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/hrt.2003.022707
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