Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis

Objective: To test the hypothesis that gene–gene interaction of the renin–angiotensin system is associated with an effect on the extent of coronary atherosclerosis. Setting and results: A cohort of 1162 patients with coronary artery disease were genotyped for genetic polymorphisms in the renin–angio...

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Bibliographic Details
Main Authors: Ye, S, Dhillon, S, Seear, R, Dunleavey, L, Day, L B, Bannister, W, Day, I N M, Simpson, I
Format: Artigo
Language:Inglês
Published: Copyright 2003 by Heart 2003
Subjects:
Cardiovascular Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1767923/
https://ncbi.nlm.nih.gov/pubmed/12975417
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