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bfr1+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily.

We have isolated a Schizosaccharomyces pombe gene, bfr1+, which on a multicopy plasmid vector, pDB248', confers resistance to brefeldin A (BFA), an inhibitor of intracellular protein transport. This gene encodes a novel protein of 1,531 amino acids with an intramolecular duplicated structure, each h...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Nagao, K, Taguchi, Y, Arioka, M, Kadokura, H, Takatsuki, A, Yoda, K, Yamasaki, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176770/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883711/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.6.1536-1543.1995
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