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Preparation of N-(t)Boc L-glutathione dimethyl and di-tert-butyl esters: versatile synthetic building blocks

The title L-glutathione derivatives, containing acid- and base-labile esters, respectively, were obtained in good overall yields. N-(t)Boc L-glutathione dimethyl ester was prepared via Fischer esterification of L-glutathione disulfide (GSSG) using HCl in dry methanol, protection of the amine with (t...

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Autors principals: Falck, J. R., Sangras, Bhavani, Capdevila, Jorge H.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766940/
https://ncbi.nlm.nih.gov/pubmed/17070060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.10.022
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