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Biological role of interleukin 1 receptor antagonist isoforms
The interleukin 1 receptor antagonist (IL1Ra) family of molecules now includes one secreted isoform (sIL1Ra) and three intracellular isoforms (icIL1Ra1, 2, and 3). Extensive evidence indicates that the sole biological function of sIL1Ra seems to be to competitively inhibit IL1 binding to cell-surfac...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1766634/ https://ncbi.nlm.nih.gov/pubmed/11053091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.59.suppl_1.i60 |
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