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DNA folding and melting observed in real time redefine the energy landscape

We report real-time observations of the folding and melting of DNA by probing two active sites of a hairpin structure, the bases and the stem end, and using an ultrafast T-jump. Studies at different initial temperatures (before, during, and after melting) provide the time scale of water heating (<...

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Autors principals: Ma, Hairong, Wan, Chaozhi, Wu, Aiguo, Zewail, Ahmed H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766338/
https://ncbi.nlm.nih.gov/pubmed/17215374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610028104
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