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A mutation in either dsbA or dsbB, a gene encoding a component of a periplasmic disulfide bond-catalyzing system, is required for high-level expression of the Bacteroides fragilis metallo-beta-lactamase, CcrA, in Escherichia coli.

The metallo-beta-lactamase gene, ccrA, from Bacteroides fragilis is functionally expressed in Escherichia coli only in the presence of a genomic mutation in iarA or iarB (increased ampicillin resistance), identified in this study as dsbA or dsbB, respectively. DsbA and DsbB are components of a perip...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:J Bacteriol
Үндсэн зохиолчид: Alksne, L E, Keeney, D, Rasmussen, B A
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Microbiology (ASM) 1995
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7814337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.177.2.462-464.1995
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