Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR

The role of the cystic fibrosis transmembrane conductance regulator (CFTR) as a cAMP-dependent chloride channel on the apical membrane of epithelia is well established. However, the processes by which CFTR is regulated on the cell surface are not clear. Here we report the identification of a protein...

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Bibliografiska uppgifter
Huvudupphovsmän: Thelin, William R., Chen, Yun, Gentzsch, Martina, Kreda, Silvia M., Sallee, Jennifer L., Scarlett, Cameron O., Borchers, Christoph H., Jacobson, Ken, Stutts, M. Jackson, Milgram, Sharon L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2007
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765518/
https://ncbi.nlm.nih.gov/pubmed/17235394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30376
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