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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
Autophagy is a lysosome-dependent degradative pathway frequently activated in tumor cells treated with chemotherapy or radiation. Whether autophagy observed in treated cancer cells represents a mechanism that allows tumor cells to survive therapy or a mechanism for initiating a nonapoptotic form of...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2007
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1765515/ https://ncbi.nlm.nih.gov/pubmed/17235397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28833 |
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