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Mechanism of tRNA-dependent editing in translational quality control

Protein synthesis requires the pairing of amino acids with tRNAs catalyzed by the aminoacyl-tRNA synthetases. The synthetases are highly specific, but errors in amino acid selection are occasionally made, opening the door to inaccurate translation of the genetic code. The fidelity of protein synthes...

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Autores principales: Ling, Jiqiang, Roy, Hervé, Ibba, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765480/
https://ncbi.nlm.nih.gov/pubmed/17185419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606272104
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