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Reengineering CCA-adding enzymes to function as (U,G)- or dCdCdA-adding enzymes or poly(C,A) and poly(U,G) polymerases
CCA-adding enzymes build and repair the 3′-terminal CCA sequence of tRNA. These unusual RNA polymerases use either a ribonucleoprotein template (class I) or pure protein template (class II) to form mock base pairs with the Watson–Crick edges of incoming CTP and ATP. Guided by the class II Bacillus s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1765476/ https://ncbi.nlm.nih.gov/pubmed/17179213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606961104 |
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