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Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25

Malaria is a leading cause of morbidity and mortality, estimated to cause >1 million childhood deaths annually. Plasmodium falciparum causes the most severe form of the disease. There is as yet no licensed vaccine for this disease, despite over a half century of research. In this study, we invest...

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Hlavní autoři: Kubler-Kielb, Joanna, Majadly, Fathy, Wu, Yimin, Narum, David L., Guo, Chunyan, Miller, Louis H., Shiloach, Joseph, Robbins, John B., Schneerson, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1765452/
https://ncbi.nlm.nih.gov/pubmed/17190797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609885104
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